Full description. On this 9.5-hour excursion, you’ll be picked up at your Prague hotel (depending on the option selected) and head off on a drive to the largest and most popular spa town in the Czech Republic. The history of this Bohemian town dates back to the 14th century. Today, Karlovy Vary is also well known for its film festival, which The cheapest way to get from Tallinn to Karlovy Vary costs only 2 629 Kč, and the quickest way takes just 7 hours. Find the travel option that best suits you. The drive from Prague to Karlovy Vary is a bit under two hours if you manage to avoid traffic. Keep in mind that you will need to find and pay for parking while in the city. If you want to rent a car for your Karlovy Vary day trip, then we suggest browsing Rentalcars.com in order to find great deals across a number of different car hire companies. Check Out the Hot Spring Colonnade and Its Resident Geyser. Built in the 1970s the Hot Spring Colonnade certainly isn’t the most attractive building in Karlovy Vary but it’s still worth visiting. The building is home to the town’s warmest hot spring running at 162° F and a geyser that spurts water 40 feet into the air. Car ferry, train, bus • 30h 33m. Take the car ferry from Dublin to Holyhead. Take the train from Holyhead to London Euston. Take the train from London St Pancras Intl to Brussel-Zuid / Bruxelles-Midi Eil. Take the train from Brussel-Zuid/Midi to Praha hl.n. Take the bus from Prague to Karlovy Vary 854. 8 776 Kč - 19 508 Kč. Alternatively, you can take a bus from Chemnitz to Karlovy Vary via Prague in around 4h 59m. Train operators. Transdev. Die Länderbahn. City-Bahn Chemnitz GmbH. Czech Railways (ČD) How To Get To Karlovy Vary: Bus: From the UANC Florenc bus terminal, the trip is approximately 2 hours. Train: From Prague Central Railway Station to Karlovy Vary Station, it takes approximately 3.5 hours. Car: This is the easiest, fastest, and most comfortable option. The journey takes approximately an hour and a half. Located about 120 kilometers away from Prague, the spa town of Karlovy Vary is a popular destination for people looking into curative spa treatments.Spas have long been a medical tradition in the Czech Republic, with doctors often recommending everything from mineral and hot spring baths to oxygen inhalation to massages as complementary health treatments. 8NdOF.